Rapid Destruction of Apparently Compatible Red Cells

Studies on the Destruction of Red Blood Cells

By SHU CHU SHEN, M.D., ELEANOR M. FLEMING, A.B. AND W. B. CASTLE, M.D. I T IS well known that in fresh preparations of the blood of patients with sicklemia the erythrocytes can be sickled immediately by displacement of the oxygen from the hemoglobin, for example, by carbon dioxide or by nitrogen. These sickled cells can he no less rapidly restored to their normal form when the blood is reexpose...

Introduction of an Experimental Model for the Rapid Destruction of Hair Cells: the Use of Dpoaes in Assessment of Rat Ear Function

Purpose: the aim of thos survey is establishment of an animal model through which a rapid distortion of the hair cell of cochlea administering amikacin and furosemide and using distortion product otoacoustic emission (DPOAE) the functioning of rat’s ear would be assessed.Materials and Methods: Forty-eight male Sprague dawley rats (with average of weight 200-250g, 12 weeks post natal) were rando...

Effect of two inbreeding generations on agronomic traits of felf-compatible red clover

Destruction in the Presence of Serum of Red Cells Coated With Antibody

In order to determine the conditions under which monocytes are able to destroy red cells coated with antibody in vitro in the presence of fluid-phase IgG, human peripheral blood monocytes and red cells coated with IgG anti-D antibody were incubated in media containing lgG (neat serum or medium containing 1000 tg/ml of purified IgGI). Although phagocytosis was markedly inhibited in media contain...

Kinetics, distribution, and sites of destruction of indium-111 oxine labelled red cells in haemolytic anaemia.

The survival of red cells labelled with indium-111 oxine in the circulation was determined. In vivo distribution at equilibrium and sites of deposition at the T50In--that is, the half life of labelled red cells--were quantitated with a scintillation camera and computer assisted image analysis. Although the rate of elution. Of 111In from the red cells was higher than that of chromium-51-disodium...